TTR Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18211
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Amyloid polyneuropathy,Amyloidosis I,ATTR,Carpal tunnel syndrome 1,CTS,CTS1,Dysprealbuminemic euthyroidal hyperthyroxinemia,Dystransthyretinemic hyperthyroxinemia,Epididymis luminal protein 111,HEL111,HsT2651,PALB,Prealbumin amyloidosis type I,Prealbumin,Prealbumin Thyroxine-binding,Senile systemic amyloidosis,TBPA,Thyroxine binding prealbumin,Transthyretin,TTHY,TTR,TTR protein,TTR抗体 |
| Swissprot | P02766 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human TTR |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
| Concentration | 0.72mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted. Cytoplasm. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Transthyretin (TTR) is a plasma transport protein for thyroxine and retinol,through the association with retinol-binding protein. It is a homotetrameric protein synthesized mainly in liver,choroid plexus,retinal pigment epithelium,and pancreas.Within the CNS,TTR is the only known protein synthesized solely by the choroid plexus. Mutant and wildtype TTR give rise to various forms of amyloid deposition (amyloidosis). Defects in TTR are the cause of amyloidosis transthyretin-related (AMYL-TTR),hyperthyroxinemia dystransthyretinemic euthyroidal (HTDE) and carpal tunnel syndrome type 1 (CTS1). In addition,positive immunostaining for TTR has been reported as a sensitive diagnostic marker of choroid plexus tumors. (22103483) |
Images
Western blot analysis of Mouse serum using TTR Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TTR Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TTR Polyclonal Antibody at dilution of 1:50(×200)
