TXN Polyclonal Antibody
规格: | / 60μL / 120μL / 200μL |
价格: | / ¥1380 / ¥2220 / ¥3580 |
货号:E-AB-62251
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
Synonyms | TXN,TRDX,TRX,TRX1,TXN抗体 |
Swissprot | P10599 |
Source | Rabbit |
Reactivity | Human,Mouse |
Immunogen | A synthetic peptide of human TXN (NP_003320.2). |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,, 1:500-1:2000;IHC,, 1:50-1:200; |
Concentration | 1 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. Cytoplasm. Secreted. Secreted by a leaderless secretory pathway. Predominantly in the cytoplasm in non irradiated cells. Radiation induces translocation of TRX from the cytoplasm to the nucleus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20°C. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Background | The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. |