UBA7 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52436
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | D8,MGC12713,UBA1,ubiquitin activating enzyme E1 homolog B,UBA1B,UBA7,UBA7,ubiquitin activating enzyme E1,UBA7,Ube 1L,UBE 2,UBE1L,UBE2,Ubiquitin activating enzyme 2,Ubiquitin activating enzyme E1 homolog,Ubiquitin Activating Enzyme E1 Like,Ubiquitin activating enzyme E1 related protein,Ubiquitin-activating enzyme 7,Ubiquitin-activating enzyme E1 homolog,ubiquitin-activating enzyme-2,ubiquitin-like modifier activating enzyme 7,Ubiquitin-like modifier-activating enzyme 7,UBA7抗体 |
| Swissprot | P41226 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Fusion protein of human UBA7 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytosol,Nucleus,nucleoplasm,Other locations:cytoplasm |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. |
