UBR4 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19599
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | 600 kDa retinoblastoma protein associated factor,600 kDa retinoblastoma protein-associated factor,E3 ubiquitin-protein ligase UBR4,KIAA0462,KIAA1307,N-recognin-4,p600,RBAF600,Retinoblastoma associated factor 600 like protein,Retinoblastoma associated factor of 600 kDa,Retinoblastoma-associated factor 600,Retinoblastoma-associated factor of 600 kDa,Ubiquitin protein ligase E3 component n recognin 4,UBR4,UBR4,Zinc finger UBR1 type protein 1,Zinc finger UBR1-type protein 1,Zinc finger, UBR1 type 1,ZUBR 1,ZUBR1,UBR4抗体 |
Swissprot | Q5T4S7 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human UBR4 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:40-1:200 |
Concentration | 1.1mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Membrane. Cytoplasm. Cytoplasm>cytoskeleton. Nucleus. Concentrates at the leading edge of membrane structures involved in actin motility. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | The protein encoded by this gene is an E3 ubiquitin-protein ligase that interacts with the retinoblastoma-associated protein in the nucleus and with calcium-bound calmodulin in the cytoplasm. The encoded protein appears to be a cytoskeletal component in the cytoplasm and part of the chromatin scaffold in the nucleus. In addition, this protein is a target of the human papillomavirus type 16 E7 oncoprotein. |