UBXN1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18676
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | 2B28,4930455J02Rik,D19Ertd721e,MGC124706,MGC6696,mY33K,Protein 2B28,RGD1309471,SAKS1,SAPK substrate protein 1,T25529,UBA/UBX 33.3 kDa protein,UBX domain containing protein 1,UBX domain protein 1,UBXD10,UBXN1,UBXN1抗体 |
| Swissprot | Q04323 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Full length fusion protein |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:40-1:200; |
| Concentration | 1.2mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. |
Images
Western blot analysis of Mouse brain tissue Hela and HEPG2 cell lysates using UBXN1 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using UBXN1 Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using UBXN1 Polyclonal Antibody at dilution of 1:35(×200)
