UCN3 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-17833
宿主: Rabbit
反应性: H
应用: IHC
Overview
Synonyms | MGC119002,OTTHUMP00000018999 ,Prepro urocortin 3,SCP,SPC,Stresscopin ,Ucn III ,UCN3 ,UCN3 urocortin 3 stresscopin,UCNIII,Urocortin 3,Urocortin 3 stresscopin,Urocortin III,UCN3抗体 |
Swissprot | Q969E3 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Synthetic peptide of human UCN3 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:300 |
Concentration | 1.4mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite. |