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UCN3 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-17833

宿主: Rabbit

反应性: H

应用: IHC

  • 详情
  • Overview

    Synonyms MGC119002,OTTHUMP00000018999 ,Prepro urocortin 3,SCP,SPC,Stresscopin ,Ucn III ,UCN3 ,UCN3 urocortin 3 stresscopin,UCNIII,Urocortin 3,Urocortin 3 stresscopin,Urocortin III,UCN3抗体
    Swissprot Q969E3
    Source Rabbit
    Reactivity Human
    Immunogen Synthetic peptide of human UCN3
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:300
    Concentration 1.4mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Secreted
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite.
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