UCP2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-17512
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | BMIQ4,Mitochondrial uncoupling protein 2,SLC25A8,Solute carrier family 25 member 8,UCP 2,ucp2,UCP2,UCPH,Uncoupling protein 2,Uncoupling protein 2 mitochondrial proton carrier,UCP2抗体 |
Swissprot | P55851 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human UCP2 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:200-1000;IHC,,1:10-50; |
Concentration | 2.1 mg/mL |
Clonality | Polyclonal |
Properties
Tissue specificity | Widely expressed in adult human tissues, including tissues rich in macrophages. Most expressed in white adipose tissue and skeletal muscle. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Background | Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. |