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UCP2 Polyclonal Antibody

规格: / 60μL / 120μL / 200μL
价格: / ¥1380 / ¥2220 / ¥3300

货号:E-AB-70257

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms BMIQ4,Mitochondrial uncoupling protein 2,SLC25A8,Solute carrier family 25 member 8,UCP 2,ucp2,UCP2,UCPH,Uncoupling protein 2,Uncoupling protein 2 mitochondrial proton carrier,UCP2抗体
    Swissprot P55851,P70406,P56500
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen KLH conjugated Synthetic peptide corresponding to Mouse UCP2
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:200-1:600
    Concentration 0.62 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Mitochondrion inner membrane.
    Tissue specificity Widely expressed in adult human tissues, including tissues rich in macrophages. Most expressed in white adipose tissue and skeletal muscle.Highest expression level in oviduct epithelium.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
    Background Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP).UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak.UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane.They also reduce the mitochondrial membrane potential in mammalian cells.
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