USP14 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18519
宿主: Rabbit
反应性: H,M
应用: WB
Overview
| Synonyms | Deubiquitinating enzyme 14,TGT,tRNA guanine transglycosylase 60 kD subunit,tRNA guanine transglycosylase,Ubiquitin carboxyl terminal hydrolase 14,Ubiquitin carboxyl-terminal hydrolase 14,Ubiquitin specific peptidase 14,Ubiquitin specific processing protease 14,Ubiquitin specific protease 14,Ubiquitin thiolesterase 14,Ubiquitin-specific-processing protease 14,UBP14,USP 14,USP14,USP14抗体 |
| Swissprot | P54578 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human USP14 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.7mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Cell membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
