Vanin‑1 Polyclonal Antibody
规格: | / 20μL / 50μL / 100μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-40574
宿主: Rabbit
反应性: H
应用: WB
Overview
Synonyms | VNN1,Pantetheinase,Pantetheinehydrolase,Tiff66,Vascularnon-inflammatorymolecule1(Vanin-1) |
Swissprot | O95497 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Recombinant Human Vanin‑1 protein expressed by E.coli. |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:1000-2000; |
Concentration | 3.5mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cellmembrane,Secreted |
Isotype | IgG |
Purification | Antigen Affinity Purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
Background | Vanin-1 (VNN1) is a member of the biotinidase family and is expressed at the cell surface in epithelial cells . VNN1 is also known as vascular non‑inflammatory molecule 1. It does not possess biotinidase activity, but is a pantetheinase that catalyzes the hydrolysis of pantetheine to pantothenic acid (vitamin‑B5) and cysteamine . VNN1 is considered to be a potential biomarker for the acute kidney injury and a target for therapeutic intervention in inflammatory bowel disease . |