VCAM1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-18302
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | CD106,CD106 Antigen,INCAM 100,INCAM-100,L1CAM,MGC99561,V-CAM 1,Vascular Cell Adhesion Molecule 1,Vascular cell adhesion protein 1,VCAM 1,VCAM-1,VCAM1,VCAM1,VCAM1抗体 |
Swissprot | P19320 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Fusion protein of human VCAM1 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:25-1:100 |
Concentration | 0.6mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Membrane. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | Vascular cell adhesion molecule 1 (VCAM1),also known as CD106,is a transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. VCAM1 is expressed by cytokine-activated endothelium,interacts with integrin VLA4 (α4β1) present on the surface of leukocytes,and mediates both adhesion and signal transduction. It is also expressed either constitutively or inducibly in a variety of other cell types,including vascular smooth muscle cells,differentiating skeletal muscle cells,renal and neural epithelial cells,macrophages (Kupffer cells),dendritic cells,and bone marrow stromal cells . |