VCAM1 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70284
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | CD106,CD106 Antigen,INCAM 100,INCAM-100,L1CAM,MGC99561,V-CAM 1,Vascular Cell Adhesion Molecule 1,Vascular cell adhesion protein 1,VCAM 1,VCAM-1,VCAM1,VCAM1,VCAM1抗体 |
| Swissprot | P29533 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein corresponding to Mouse VCAM-1 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.63 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Tissue specificity | Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue. Expressed in the bone marrow.Highest expression level in spleen. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | Vascular cell adhesion molecule 1 (VCAM1),also known as CD106,is a transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. VCAM1 is expressed by cytokine-activated endothelium,interacts with integrin VLA4 (α4β1) present on the surface of leukocytes,and mediates both adhesion and signal transduction. It is also expressed either constitutively or inducibly in a variety of other cell types,including vascular smooth muscle cells,differentiating skeletal muscle cells,renal and neural epithelial cells,macrophages (Kupffer cells),dendritic cells,and bone marrow stromal cells . |
