VCP Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18489
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | 15S Mg(2+) ATPase p97 subunit,15S Mg(2+)-ATPase p97 subunit,ALS14,ATPase p97,CDC48,IBMPFD,MGC131997,MGC148092,MGC8560,p97,TER ATPase,TERA,TERA,Transitional endoplasmic reticulum ATPase,Valosin containing protein,Valosin-containing protein,VCP,Yeast Cdc48p homolog,VCP抗体 |
| Swissprot | P55072 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human VCP |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:30-1:150; |
| Concentration | 0.5mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm>cytosol. Nucleus. Present in the neuronal hyaline inclusion bodies specifically found in motor neurons from amyotrophic lateral sclerosis patients. Present in the Lewy bodies specifically found in neurons from Parkinson disease patients. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | VCP(Valosin-containing protein) belongs to the AAA ATPase family.VCP was first identified as a result of attempts to clone a putative peptide hormone called valosin. It was found that the cloned cDNA encoded a ubiquitously expressed 90 kDa cytosolic protein,termed VCP,which showed none of the characteristics of a peptide hormone precursor.Defects in VCP are the cause of inclusion body myopathy with early-onset Paget disease and frontotemporal dementia (IBMPFD) and amyotrophic lateral sclerosis type 14 with or without frontotemporal dementia (ALS14) |
Images
Western blot analysis of 231 Hela A549 A431 HEPG2 Jurkat and K562 cell lysates using VCP Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using VCP Polyclonal Antibody at dilution of 1:30(×200)
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using VCP Polyclonal Antibody at dilution of 1:30(×200)
