VE-Cadherin Monoclonal Antibody
| 规格： | / 20μL / 60μL / 120μL |
| 价格： | / ￥580 / ￥1420 / ￥2310 |
货号：E-AB-22244
宿主: Mouse
反应性: H,M,R
应用: IHC-p
Overview
| Synonyms | 7B 4,7B4,7B4 antigen,CADH5,Cadherin 5,Cadherin 5 type 2,Cadherin 5,type 2 (vascular endothelium),Cadherin 5,type 2,VE cadherin (vascular epithelium),cadherin,vascular endothelial,cadherin,vascular endothelial,1,Cadherin-5,Cadherin5,CD 144,CD144,CD144 antigen,CDH 5,CDH5,CDH5 protein,Endothelial specific cadherin,FLJ17376,OTTHUMP00000174777,Vascular endothelial cadherin,Vascular epithelium cadherin,VE Cad,VE-cadherin,VEC,VE-Cadherin Mouse (8E5)抗体 |
| Swissprot | P33151 |
| Source | Mouse |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic Peptide of VE-Cadherin |
| Application | IHC-p(Detection kit: E-IR-R213) |
| Recommended dilution | IHC 1:100-200 |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Cellular localization | Cell junction. Cell membrane. Found at cell-cell boundaries and probably at cell-matrix boundaries. |
| Tissue specificity | Endothelial tissues and brain. |
| Clone No | Clone:8E5 |
|---|---|
| Isotype | IgG |
| Purification | Protein A purification |
| Conjugation | VE-Cadherin Mouse Monoclonal Antibody |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
| Background | This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. |
