VE-Cadherin Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12772
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | 7B 4,7B4,7B4 antigen,CADH5,Cadherin 5,Cadherin 5 type 2,Cadherin 5,type 2 (vascular endothelium),Cadherin 5,type 2,VE cadherin (vascular epithelium),cadherin,vascular endothelial,cadherin,vascular endothelial,1,Cadherin-5,Cadherin5,CD 144,CD144,CD144 antigen,CDH 5,CDH5,CDH5 protein,Endothelial specific cadherin,FLJ17376,OTTHUMP00000174777,Vascular endothelial cadherin,Vascular epithelium cadherin,VE Cad,VE-cadherin,VEC,CDH5抗体 |
| Swissprot | P33151 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human CDH5 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell junction. Cell membrane. Found at cell-cell boundaries and probably at cell-matrix boundaries. |
| Tissue specificity | Endothelial tissues and brain. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. |
