VE-Cadherin Polyclonal Antibody(Capture/Detector)
| 规格： | / 25μg / 100μg |
| 价格： | / ￥800 / ￥2100 |
货号：AN000140P
货期：咨询
宿主: Rabbit
反应性: H
应用: ELISA Capture/Detector
Overview
| Synonyms | CDH5;CD144;Cadherin-5;7B4 antigen;VascuLar endotheLiaL cadherin (VE-cadherin) |
| Swissprot | P33151 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant Human VE-Cadherin protein expressed by E.coli |
| Application | ELISA Capture/Detector |
| Recommended dilution | ELISA Capture,,2-8 μg/mL;ELISA Detector,,0.1-0.4 μg/mL |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at 4°C Valid for 1 month or -20°C Valid for 12 months,Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Storage buffer | Sterile PBS,pH 7.4 |
| Background | Cadherins are calcium-dependent cell adhesion proteins.They preferentially interact with themselves in a homophilic manner in connecting cells,cadherins may thus contribute to the sorting of heterogeneous cell types.This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.It associates with alpha-catenin forming a link to the cytoskeleton.Acts in concert with KRIT1 and PAlS1 to establish and maintain correct endothelial cell polarity and vascular lumen.These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B.Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ,PARD3,TIAM1 and RAP1B to the cell junction. |
