VNN1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-53205
宿主: Rabbit
反应性: H
应用: IF
Overview
Synonyms | HDLCQ8,High density lipoprotein cholesterol level quantitative trait locus 8,included,Pantetheinase,Pantetheine hydrolase,Tiff66,V-1,Vanin 1,Vanin-1,Vannin 1,Vascular non inflammatory molecule 1,Vascular non-inflammatory molecule 1,VNN 1,VNN1,VNN1,VNN1抗体 |
Swissprot | O95497 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Synthetic peptide of human VNN1 |
Application | IF |
Recommended dilution | IF,,1:100-1:500 |
Concentration | 1.7mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell membrane. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24. |