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VNN1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-53205

宿主: Rabbit

反应性: H

应用: IF

  • 详情
  • Overview

    Synonyms HDLCQ8,High density lipoprotein cholesterol level quantitative trait locus 8,included,Pantetheinase,Pantetheine hydrolase,Tiff66,V-1,Vanin 1,Vanin-1,Vannin 1,Vascular non inflammatory molecule 1,Vascular non-inflammatory molecule 1,VNN 1,VNN1,VNN1,VNN1抗体
    Swissprot O95497
    Source Rabbit
    Reactivity Human
    Immunogen Synthetic peptide of human VNN1
    Application IF
    Recommended dilution IF,,1:100-1:500
    Concentration 1.7mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.
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