VRK3 Polyclonal Antibody
| 规格: | / 20μL / 60μL / 120μL / 200μL |
| 价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-52423
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | VRK3,Inactive serine/threonine-protein kinase VRK3,Serine/threonine-protein pseudokinase VRK3,Vaccinia-related kinase 3,VRK3抗体 |
| Swissprot | Q8IV63 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human VRK3 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus,nucleolus,Other locations:cytoplasm,intracellular membrane-bounded organelle |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases.In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis.In vitro assays indicate the protein lacks phosphorylation activity.The protein, however, likely retains its substrate binding capability.This gene is widely expressed in human tissues and its protein localizes to the nucleus.Alternative splicing results in multiple transcripts encoding different isoforms. |
