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VRK3 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-52423

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms VRK3,Inactive serine/threonine-protein kinase VRK3,Serine/threonine-protein pseudokinase VRK3,Vaccinia-related kinase 3,VRK3抗体
    Swissprot Q8IV63
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Fusion protein of human VRK3
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:30-1:150
    Concentration 0.6mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus,nucleolus,Other locations:cytoplasm,intracellular membrane-bounded organelle
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases.In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis.In vitro assays indicate the protein lacks phosphorylation activity.The protein, however, likely retains its substrate binding capability.This gene is widely expressed in human tissues and its protein localizes to the nucleus.Alternative splicing results in multiple transcripts encoding different isoforms.
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