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WEE1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19363

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms DKFZp686I18166,EC 2.7.10.2,FLJ16446,MGC105683,OTTHUMP00000231338,OTTHUMP00000231339,Wee 1,WEE 1 homolog 1 (S. pombe),WEE1,WEE1 homolog (S. pombe),Wee1 homolog,WEE1 homolog S. pombe,Wee1 like protein kinase,Wee1 tyrosine kinase,Wee1+ homolog,Wee1+ S. pombe homolog,WEE1,S. pombe,homolog of,WEE1,somatic,Wee1-like protein kinase,WEE1,WEE1A,Wee1A kinase,WEE1hu,WEE1抗体
    Swissprot P30291
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human WEE1
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:30-1:150
    Concentration 1.3mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.WEE1 (WEE1 G2 Checkpoint Kinase) is a Protein Coding gene. Among its related pathways are PLK1 signaling events and Cell cycle Role of 14-3-3 proteins in cell cycle regulation. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is WEE2.
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