XPO1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-17839
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Chromosome region maintenance 1 protein homolog,CRM 1,CRM1 homolog,DKFZp686B1823,emb,Exp 1,Exp1,Exportin 1,Exportin-1,Exportin1,XPO 1,xpo1,XPO1,XPO1抗体 |
| Swissprot | O14980 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human XPO1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:30-1:150; |
| Concentration | 1.1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus>nucleoplasm. Nucleus>Cajal body. Nucleus>nucleolus. Located in the nucleoplasm, Cajal bodies and nucleoli. Shuttles between the nucleus/nucleolus and the cytoplasm. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport.Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs.It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2.This protein also regulates NFAT and AP-1. |
Images
Western blot analysis of Hela K562 and HEPG2 cell lysates using XPO1 Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using XPO1 Polyclonal Antibody at dilution of 1:40(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using XPO1 Polyclonal Antibody at dilution of 1:40(×200)
