ZAK Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-53217
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | AZK,Cervical cancer suppressor gene 4 protein,HCCS 4,HCCS-4,HCCS4,Human cervical cancer suppressor gene 4 protein,Leucine zipper and sterile alpha motif containing kinase,Leucine zipper- and sterile alpha motif-containing kinase,Mitogen activated protein kinase kinase kinase MLT,Mitogen-activated protein kinase kinase kinase MLT,Mixed lineage kinase 7,Mixed lineage kinase related kinase,Mixed lineage kinase related kinase MRK beta,Mixed lineage kinase with a leucine zipper and a sterile alpha motif,Mixed lineage kinase-related kinase,MLK 7,MLK like mitogen activated protein triple kinase,MLK related kinase,MLK-like mitogen-activated protein triple kinase,MLK-related kinase,MLK7,Mlklak,MLT,MLTK,MRK,Sterile alpha motif and leucine zipper containing kinase AZK,Sterile alpha motif- and leucine zipper-containing kinase AZK,Zak,ZAK 抗体 |
Swissprot | Q9NYL2 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human ZAK |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:200 |
Concentration | 1.2mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm. Nucleus. Translocates to the nucleus upon ultraviolet B irradiation. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM).This magnesium-binding protein forms homodimers and is located in the cytoplasm.The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. |