ZBTB10 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19551
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | FLJ12752,OTTHUMP00000207119,RINZF,RINZFC,ZBT10,ZBTB10,Zinc finger and BTB domain containing protein 10,Zinc finger and BTB domain-containing protein 10,Zinc finger protein RIN ZF,ZBTB10抗体 |
| Swissprot | Q96DT7 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human ZBTB10 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:300; |
| Concentration | 1.7mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | RINZF, also known as ZBTB10 (zinc finger and BTB domain containing protein 10), is a 847 amino acid protein that contains one BTB/POZ domain and two C2H2-type zinc fingers. Localized to the nucleus, RINZF is believed to play a role in transcriptional regulation. Specifically, RINZF is capable of binding to the CACC element of the Gastrin promoter. In this regard, RINZF competes with Sp1 for CACC binding and interferes with Sp1 transactivation, thereby regulating Gastrin gene expression. The rat RINZF protein shares 98% homology with the human RINZF protein, suggesting that RINZF is a conserved protein. Due to alternative splicing events, two RINZF isoforms exist. In addition, RINZF may be phosphorylated by ATR or ATM upon DNA damage. |
Images
Western blot analysis of Jurkat cell lysate using ZBTB10 Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using ZBTB10 Polyclonal Antibody at dilution of 1:100(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using ZBTB10 Polyclonal Antibody at dilution of 1:100(×200)
