ZC3HAV1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19553
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | ADP ribosyltransferase diphtheria toxin like 13,ARTD13,FLB6421,PARP13,ZAP,ZC3H2,ZC3HAV 1,Zc3hav1,ZC3HDC 2,ZC3HDC2,ZCCHV,Zinc finger antiviral protein,Zinc finger CCCH domain containing protein 2,Zinc finger CCCH domain-containing antiviral protein 1,Zinc finger CCCH domain-containing protein 2,Zinc finger CCCH type antiviral 1,Zinc finger CCCH type antiviral protein 1,Zinc finger CCCH-type antiviral protein 1,ZC3HAV1抗体 |
| Swissprot | Q7Z2W4 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human ZC3HAV1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:45-1:300 |
| Concentration | 1.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. Localizes in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | he zinc-finger antiviral protein (ZAP) was originally identifed from a rat cDNA library due to its conferring resistance to retroviruses. ZC3HAV1 is a CCCH-type zinc finger protein,it may primarily function to inhibit viral gene expression and induce an innate immunity to viral infection. Alternative splicing occurs at this locus and two variants,each encoding distinct isoforms. |
