ZFAND5 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18321
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | AN1-type zinc finger protein 5,ZA20D2,ZFAN5,Zfand5,ZFAND5A,zinc finger A20 domain containing 2 ,Zinc finger A20 domain containing protein 2 ,Zinc finger A20 domain-containing protein 2,zinc finger AN1 type domain 5,Zinc finger protein 216,ZNF216,ZFAND5抗体 |
| Swissprot | O76080 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Full length fusion protein |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:25-1:100; |
| Concentration | 1.4mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation. |
Images
Western blot analysis of Mouse fat tissue lysate using ZFAND5 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ZFAND5 Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using ZFAND5 Polyclonal Antibody at dilution of 1:35(×200)
