ZFYVE19 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-53235
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
Synonyms | Abscission/NoCut checkpoint regulator,ANCHR,MLL partner containing FYVE domain,MPFYVE,ZFY19,ZFYVE 19,Zfyve19,Zinc finger FYVE domain containing protein 19,Zinc finger FYVE domain-containing protein 19,Zinc finger FYVE type containing 19,Zinc finger,FYVE domain containing 19,ZFYVE19 抗体 |
Swissprot | Q96K21 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Synthetic peptide of human ZFYVE19 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
Concentration | 2mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoskeleton,centrosome,Other locations:cleavage furrow,cytoplasm,Flemming body,midbody |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | ZFYVE19 (zinc finger, FYVE domain containing 19), also known as MPFYVE (MLL partner containing FYVE domain), is a 471 amino acid protein that contains one FYVE-type zinc finger. Expressed in heart, brain, kidney, skeletal muscle and liver, ZFYVE19 may participate in transcriptional regulation events within the cell. Defects in the gene encoding ZFYVE19 are associated with acute myeloblastic leukemia (AML), a rapidly progressing cancer of the myeloid line of white blood cells that is characterized by fever, anemia, bone pain, shortness of breath and frequent infections. Three isoforms of ZFYVE19 exist due to alternative splicing events. |
Images
Western blot analysis of Hela cells A431 cells using ZFYVE19 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human tonsil tissue using ZFYVE19 Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ZFYVE19 Polyclonal Antibody at dilution of 1:60(×200)