ZKSCAN3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18451
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | dJ874C20.1,mszf35,SCAN-KRAB-zinc finger protein,Skz1,Zf47,Zfp-47,ZFP306,Zfp307,Zfp47,Zinc finger and SCAN domain containing protein 13,Zinc finger and SCAN domain-containing protein 13,Zinc finger protein 306,Zinc finger protein 306, isoform CRA_a,Zinc finger protein 307,Zinc finger protein 309,Zinc finger protein 47 homolog,Zinc finger protein with KRAB and SCAN domains 3,Zinc finger protein with KRAB and SCAN domains 3,Zinc finger protein zfp47 ,Zinc finger with KRAB and SCAN domains 3,ZKSC3,ZKSCAN3,ZNF309,ZSCAN13,ZSCAN35,ZKSCAN3抗体 |
| Swissprot | Q9BRR0 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human ZKSCAN3 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:40-1:250 |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas. |
