ZNF281 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18446
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | GC box binding zinc finger protein 1,GC-box-binding zinc finger protein 1,GZP1,Transcription factor ZBP-99,ZBP 99,ZBP99,zfp281,Zinc finger DNA binding protein 99,Zinc finger DNA-binding protein 99,Zinc finger protein 281,ZN281,ZNF281,ZNP 99,ZNP 99 transcription factor,ZNP99,ZNF281抗体 |
| Swissprot | Q9Y2X9 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human ZNF281 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:25-1:100; |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | ZNF281, also known as GC-box-binding zinc finger protein 1, ZBP-99 or ZNP-99 (zinc finger DNA-binding protein 99), is a zinc finger protein that belongs to the Krüppel C2H2-type zinc finger protein family. It is expressed ubiquitously at low levels with predominant expression in kidney, liver, lymphocytes and placenta. ZNF281 localizes to the nucleus and contains four C2H2-type zinc fingers. ZNF281 plays a role in repressing the transcription of a variety of genes including Gastrin and ODC (ornithine decarboxylase). In particular, ZNF281 functions by binding to the G-rich box in the enhancer region of the gene. Upon DNA damage, ZNF281 may become phosphorylated by Atm or ATR. |
Images
Western blot analysis of A549 cell using ZNF281 Polyclonal Antibody at dilution of 1:250
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ZNF281 Polyclonal Antibody at dilution of 1:30(×200)
Immunohistochemistry of paraffin-embedded Human prost ate cancer tissue using ZNF281 Polyclonal Antibody at dilution of 1:30(×200)
