ZPR1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18457
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | MGC110983,Zinc finger protein 259,Zinc finger protein ZPR1,ZNF 259,ZNF259,ZPR1,ZPR1,ZPR1抗体 |
| Swissprot | O75312 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human ZPR1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:30-1:150; |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus>nucleolus. Translocates to the nucleolus after treatment with mitogens. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | ZPR1 is a zinc finger-containing protein that is capable of binding to the intracellular tyrosine kinase domain of the epidermal growth factor receptor. Stimulation of mammalian cells with epidermal growth factor reduces ZPR1 affinity for the EGFR and leads to an accumulation of the protein in the nucleus. The ZPR1 zinc finger is necessary for its association with the EGFR. |
Images
Western blot analysis of Hela HEPG2 231 A431 and Jurkat cell lysates using ZPR1 Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ZPR1 Polyclonal Antibody at dilution of 1:40(×200)
Immunohistochemistry of paraffin-embedded Human prost ate cancer tissue using ZPR1 Polyclonal Antibody at dilution of 1:40(×200)
