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ZWINT Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-10889

宿主: Rabbit

反应性: H

应用: IHC

  • 详情
  • Overview

    Synonyms Human ZW10 interacting protein 1,HZwint 1,HZwint1,KNTC 2 AP,KNTC2AP,MGC 117174,MGC117174,ZW10 interacting kinetochore protein,ZW10 interacting protein 1,ZW10 interactor,ZW10 interactor,kinetochore protein,ZW10-interacting protein 1,ZWINT 1,ZWINT,Zwint-1,ZWINT,ZWINT1,ZWINT抗体
    Swissprot O95229
    Source Rabbit
    Reactivity Human
    Immunogen Recombinant protein of human ZWINT
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:200
    Concentration 0.5 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus. Chromosome>centromere>kinetochore. Localizes to kinetochores from late prophase to anaphase.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known.It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores.The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase.It has a uniform distribution in the cytoplasm of interphase cells.Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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